Hadn’t seen this. I don’t watch Venture Bros., but I heard he was on it.
You have to be familiar with his albums, and Bowie’s, to understand why he says “Ding dong. The queen bitch is dead.”
Edit: The thing I find most interesting about this is that it makes it look like Klaus Nomi, Iggy Pop, and David Bowie were chums. But after Klaus Nomi performed with Bowie on SNL they never talked again. The Nomi crew thought it was going to lead to bigger things.